IL5 Urothelial-Afferent Interaction : A Possible Mechanism inducing Overactive Bladder (OAB)(IL)
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چکیده
منابع مشابه
Inhibitory Effect and Possible Mechanism of Intraurethral Stimulation on Overactive Bladder in Female Rats
PURPOSE To investigate the inhibitory effect and possible mechanism of intraurethral stimulation on overactive bladder (OAB) induced by acetic acid irritation. METHODS Cystometry was performed in 13 urethane-anesthetized female rats. Intravesical infusion of 0.5% acetic acid was used to irritate the bladder and induce OAB. Multiple cystometrograms were performed with mirabegron, continuous st...
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The overactive bladder syndrome and detrusor overactivity are conditions that can have major effects on quality of life and social functioning. Antimuscarinic drugs are still first-line treatment. These drugs often have good initial response rates, but adverse effects and decreasing efficacy cause long-term compliance problems, and alternatives are needed. The recognition of the functional cont...
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Overactive bladder (OAB) is common and has a negative impact on a patient's quality of life. It is important for physicians to know how to identify and manage patients with this condition. Usually only basic clinical evaluations and a good patient history are necessary to diagnose OAB. Effective and safe oral therapy is available and can be initiated by primary care physicians.
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Overactive bladder is a condition whose prevalence increases with ageing, and which can substantially impair quality of life. It is defined by presence of urinary urgency, in the absence of other causes of similar problems. The underlying mechanisms are incompletely understood, but may include increased excitability of smooth muscle, abnormal spread of excitation through the bladder wall, incre...
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Bladder storage symptoms have a severe impact on many areas as regards the quality of life including health-related, social, psychological and working functions. Pharmacotherapy of lower urinary tract stores (LUTS) has been developed to optimize neural control of the lower urinary tract in pathologic states. The bladder can be overactive or underactive. Overactive bladder (OAB) is highly preval...
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ژورنال
عنوان ژورنال: The Japanese Journal of Urology
سال: 2006
ISSN: 0021-5287,1884-7110
DOI: 10.5980/jpnjurol.97.88